2025

Structure-function mapping of host defense peptide mimics reveals strategies for antibacterial activity and eradication of mature bacterial biofilms

Physics-Informed Graph Neural Networks for Predicting Deformation in Disordered Fibrous Materials

Reconstituting transcription–translation-coupled DNA replication within complex in vitro biological systems

Biomimetic Hierarchical Molecular Assembly of Silk‐Hydroxyapatite Composites for Near‐Native Bone Regeneration

Hierarchical Silk Fibril Networks Exhibit Structure Dependent Mechanical Performance

Yang, YH; Bai, RN; Gao, WL; Cao, LT; Ren, J; Shao, ZZ; Ling, SJ. Optimizing Biomimetic 3D Disordered Fibrous Network Structures for Lightweight, High-Strength Materials via Deep Reinforcement Learning. ADVANCED SCIENCE 2025, 12(11): 2413293.

Ma, YQ; Xia, SC; Hu, AN; Zhang, QY; Shao, ZZ; Tian, B; Lin, QR. Ultrabright contrast agents with synergistic Raman enhancements for precise intraoperative imaging and photothermal ablation of orthotopic tumor models. JOURNAL OF NANOBIOTECHNOLOGY 2025, 23(1)

Xiao, ML; Liu, W; Chen, L; Zhao, BJ; Sun, LY; Yang, WH; Yao, JR; Shao, ZZ; Ling, SJ; Chen, X. Hemostatic, Antimicrobial, and Thixotropic Hydrogels Based on Natural Silk Nanofibril/Halloysite Nanotube/Extracellular Vesicle Hybrids. ADVANCED MATERIALS TECHNOLOGIES 2025, 10(13).

Lu, X; Lin, ZD; Li, LJZ; Xu, GY; Li, DC; Gong, ZY; Wu, JD; Gao, T; Guo, XY; Xu, CP; Xia, XL; Lyu, F; Zou, F; Jiang, JY; Shao, ZZ; Ma, XS; Wang, HL; Song, J. Exosome-loaded methacrylated silk fibroin hydrogel delays intervertebral disc degeneration by DKK2-mediated mitochondrial unfolded protein response. CHEMICAL ENGINEERING JOURNAL 2025, 511.

Xiao, ML; Sun, LY; Fu, H; Yang, WH; Yao, JR; Shao, ZZ; Ling, SJ; Zhao, BJ; Chen, X. Controllable fabrication of silk fibroin porous scaffolds and their regulation on cellular behaviours. JOURNAL OF MATERIALS CHEMISTRY B 2025, 13(18): 5453-5465.

Yang, K; Zhang, JW; Zhang, C; Guan, J; Ling, SJ; Shao, ZZ. Hierarchical design of silkworm silk for functional composites. CHEMICAL SOCIETY REVIEWS 2025, 54(10): 4973-5020.

Tilieke, M; Shu, X; Chen, L; Jie, YS; Zheng, R; Zhang, Z; Numata, K; Guan, J; Shao, ZZ. Rapid UV-induced and robust methacrylated silk fibroin reinforced polyacrylamide-based triple-crosslinked hydrogels. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2025, 318(4):145266.

Xiao, ML; Sun, LY; Wu, K; Ding, YQ; Wang, PP; Mu, CC; Yao, JR; Shao, ZZ; Zhao, BJ; Chen, X. A sequential drug delivery system based on silk fibroin scaffold for effective cartilage repair. BIOACTIVE MATERIALS 2025, 49:255-270.

Liu, ZY; Tilieke, M; Zhou, Y; Ming, MD; Zhang, HT; Chen, L; Zheng, R; Jie, YS; Shu, X; Guan, J; Ling, SJ; Chen, X; Shao, ZZ. Calcium polyphosphate endows silk fibroin hydrogels with enhanced osteogenesis for bone function restoration. JOURNAL OF MATERIALS CHEMISTRY B 2025, 13(33): 10331-10342.

Lin, QR; Liu, Y; Li, YM; Li, LJZ; Vollrath, F; Ji, MB; Shao, ZZ. From Snapshot to Movie: Visualizing Native Silk Spinning Defines the Paradigm for Bio-Inspired Spinning. ADVANCED FUNCTIONAL MATERIALS 2025.

Zhong, NP; Du, LX; Bai, YL; Chen, ZC; Cai, LH; Shao, ZZ; Zhao, X. A novel 3D-printed silk fibroin/hydroxypropyl methyl cellulose scaffold with good biocompatibility and controllable degradation in vivo. JOURNAL OF BIOMATERIALS APPLICATIONS 2025, 40(5): 565-579.

Fu, Y; Li, LJZ; Ye, C; Cao, LT; Yao, JR; Chen, X; Ling, SJ; Shao, ZZ. Deep eutectic solvent infused silk fibroin gels for flexible touch sensing. JOURNAL OF MATERIALS CHEMISTRY C 2025, 13(36): 18894-18904.

Xiao, ML; Sun, LY; Fu, H; Yang, WH; Yao, JR; Shao, ZZ; Ling, SJ; Zhao, BJ; Chen, X. An Expandable Silk Fibroin/Montmorillonite Porous Scaffolds Based on Clinical Dual Hemostasis Concept and Its Application in Bone Regeneration of Tooth Extraction Sockets with Coagulation Disorders. ADVANCED HEALTHCARE MATERIALS 2025.

Xiao, ML; Liu, W; Chen, L; Zhao, BJ; Sun, LY; Yang, WH; Yao, JR; Shao, ZZ; Ling, SJ; Chen, X. Hemostatic, Antimicrobial, and Thixotropic Hydrogels Based on Natural Silk Nanofibril/Halloysite Nanotube/Extracellular Vesicle Hybrids. ADVANCED MATERIALS TECHNOLOGIES 2025, 10(13).

Xiao, ML; Sun, LY; Fu, H; Yang, WH; Yao, JR; Shao, ZZ; Ling, SJ; Zhao, BJ; Chen, X. Controllable fabrication of silk fibroin porous scaffolds and their regulation on cellular behaviours. JOURNAL OF MATERIALS CHEMISTRY B 2025, 13(18): 5453-5465.

Xiao, ML; Sun, LY; Wu, K; Ding, YQ; Wang, PP; Mu, CC; Yao, JR; Shao, ZZ; Zhao, BJ; Chen, X. A sequential drug delivery system based on silk fibroin scaffold for effective cartilage repair. BIOACTIVE MATERIALS 2025, 49:255-270.

Fu, Y; Li, LJZ; Ye, C; Cao, LT; Yao, JR; Chen, X; Ling, SJ; Shao, ZZ. Deep eutectic solvent infused silk fibroin gels for flexible touch sensing. JOURNAL OF MATERIALS CHEMISTRY C 2025, 13(36): 18894-18904.

Xiao, ML; Sun, LY; Fu, H; Yang, WH; Yao, JR; Shao, ZZ; Ling, SJ; Zhao, BJ; Chen, X. An Expandable Silk Fibroin/Montmorillonite Porous Scaffolds Based on Clinical Dual Hemostasis Concept and Its Application in Bone Regeneration of Tooth Extraction Sockets with Coagulation Disorders. ADVANCED HEALTHCARE MATERIALS 2025.

2024

Li, XY; Chen, N; Yang, GW; Shao, ZZ. Design and Preparation of Antifreeze Silk-based Bioadhesive. ACTA POLYMERICA SINICA 2024, 55(11): 1463-1475.

Yang, GW; Chen, XY; Shi, WJ; Chen, N; Liu, Y; Zhang, B; Shao, ZZ*. Facile Preparation of a Photo-Cross-Linked Silk Fibroin-Poly lonic Liquid Hydrogel with Antifreezing and lon Conductive Properties. ACS APPLIED MATERIALS & INTERFACES 2024, 16(1): 1543-1552.

Miao, BL; Wang, YS; Liu, Y; Da, GH; Wang, Y; Chen, X; Shao, ZZ*. An Interfacial-Assembled Self-Supporting Nanofilm Induced by Strong Intermolecular Interaction between Silk Fibroin and Lysozyme. ADVANCED FUNCTIONAL MATERIALS 2024, 34(16).

Zhou, B; Luo, FY; Liu, Y; Shao, ZZ*. Engineering a High-Strength and Superior-Electrolyte Wettability Silk Fibroin-Based Gel Interface Achieving Dendrite-Free Zn Anode. ACS APPLIED MATERIALS & INTERFACES 2024, 16(15): 18927-18936.

Xiao, ML; Yao, JR; Shao, ZZ; Chen, X*. Silk-Based 3D Porous Scaffolds for Tissue Engineering. ACS BIOMATERIALS SCIENCE & ENGINEERING 2024, 10(5):2827-2840.

Gao, H; Chen, N; Sun, LY; Sheng, DD; Zhong, YT; Huang, MR; Yu, CX; Yang, X; Hao, YF; Chen, SY; Shao, ZZ; Chen, J. Time-programmed release of curcumin and Zn2+2+from multi-layered RSF coating modified PET graft for improvement of graft-host integration. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2024, 272.

Wang, Y; Gao, WL; Chen, QL; Ren, J; Chen, X; Li, J; Shao, ZZ; Ling, SJ*. Mechanically modulable and human-machine interactive luminescent fiber display platforms. MRS BULLETIN 2024, 49(8): 802-816.

Gu, K; Tong, YX; Mi, RX; Leng, SY; Yao, JR; Huang, HW; Chen, X; Shao, ZZ*. The production of soluble regenerated silk fibroin powder with high molecular weight and silk protein-based materials. GIANT 2024, 19.

Chen, L; Liu, W; Xiao, ML; Sun, LY; Chen, XX; Ni, LY; Yao, JR; Shao, ZZ; Zhao, BJ; Chen, X*. Super Stable Silk Nanofibrils Prepared by an lmproved Exfoliation Method and Their Related Applications. ADVANCED MATERIALS TECHNOLOGIES 2024, 9(20).

Sun, LY; Xiao, ML; Chen, L; Ni, LY; Chen, XX; Zhang, LN; Yao, JR; Shao, ZZ; Zhao, BJ; Chen, X; Liu, YH*. Enhanced Tissue Regeneration Through Immunomodulatory Extracellular Vesicles Encapsulated in Diversified Silk-Based iniectable Hydrogels. ADVANCED HEALTHCARE MATERIALS 2024, 13(28).

Wang, ZX; Yin, XY; Zhuang, CY; Wu, K; Wang, HR; Shao, ZZ; Tian, B; Lin, H*. Injectable Regenerated Silk Fibroin Micro/Nanosphere with Enhanced Permeability and Stability for Osteoarthritis Therapy. SMALL 2024, 20(46).

Fu, Y; Lin, QR; Lan, RQ; Shao, ZZ*. Ultra-Strong Protein-Based Hydrogels via Promoting Intermolecular Entanglement of the Amorphous Region. SMALL 2024.

Bi, YF; Chen, XY; Luo, FY; Wang, XH; Chen, X; Yao, JR*; Shao, ZZ*. Magnetic silk fibroin nanospheres loaded with amphiphilic polypeptides and antibiotics for biofilm eradication. BIOMATERIALS SCIENCE 2024.

Liang, Q; Xu, Q; Yang, GW; Xu, YT; Huang, HX; Hou, ZS; Shao, ZZ; Wang, M; Sun, YL*. Femtosecond laser direct writing Bombyx mori sericin-based nanocomposites into intrinsically soft wearable micro-/nano-electronics. NANOSCALE 2024.

Chen, XY; Wen, HJ; Yao, JR; Chen, X; Wang, Y; Shao, ZZ*. Highly Water-Dispersible Spiropyran-Octapeptide Supramolecules: Efficient, Multi-processable, and Versatile Photoswitches for Time-Dependent Dual-Mode Encryption. ADVANCED FUNCTIONAL MATERIALS 2024.

Chen, QL; Wu, K; Yao, JR; Shao, ZZ; Chen, X*. Adhesive silk fibroin/magnesium composite films and their application for removable wound dressing. BIOMATERIALS SCIENCE 2024.

Liu, Y; Song, YF; Wang, J; Shao, ZZ*. Elevating Postinjection Stability in Silk Nanofibril Hydrogels to Prevent Intervertebral Disc Degeneration. BIOMACROMOLECULES 2024.

Chen, Qiaolin; Yang, Shuo; Wang, Yang, Peng, Ruoxuan; Gao, Wenli; Cao, Leitao; Yao.Jinrong; Shao, Zhengzhong; Chen, Xin*; Ling, Shengiie*. Flexible Photoacoustic Device Integrating Electroluminescence,Piezoelectric Vibration, andPressure Sensing. ACS applied materials & interfaces 2024.

孙奕，吴伟，文飘，任婧，郑可*，高文丽*，凌盛杰*，基于蒸腾驱动的柞蚕超纤纸电化学传感器的设计、制备及其溶剂在线鉴别应用研究，高分子学报，2024，1-12

Wenli Gao, Qianqian Jiang, Ying Guan, Huahong Huang, Shengquan Liu, Shengjie Ling*, Liang Zhou*, Transfer learning improves predictions in lignin content of Chinese fir based on Raman spectra. International Journal of Biological Macromolecules, 2024, 269, 132147

Lu Nie#, Jinling Zhu#, Xiaoyan Wu, Mengtian Zhang, Xiao Xiao, Runhua Gao, Xinru Wu, Yanfei Zhu, Shaojie Chen, Zhiyuan Han, Yi Yu, Shaogang Wang, Shengjie Ling*, Guangmin Zhou*, A Large-scale fabrication of flexible, ultrathin, and robust solid electrolyte for solid-state lithium-sulfur batteries, Advanced Materials, 2024, 2400115

Wan-Qiu Liu, Xiangyang Ji, Fang Ba, Yufei Zhang, Huiling Xu, Shuhui Huang, Xiao Zheng, Yifan Liu*, Shengjie Ling*, Michael C. Jewett* and Jian Li*, Cell-free biosynthesis and engineering of ribosomally synthesized lanthipeptides, Nature Communications, 2024, 15, 4336

Weiming Zhou#; Sijia Sun; Yuting Zhang; Shuaiqi Wang; Shuai Zhang; Shengjie Ling*; Changtong Mei; Pan, Mingzhu, Dynamic organic-inorganic hybrid network for self-healing and self-powered fire hazard sensor, Chemical Engineering Journal, 2024, 484: 149331

Chenchen Wu, Yu Duan, Lintao Yu, Yao Hu, Chenxi Zhao, Chunwang Ji, Xiangdong Guo, Shu Zhang, Xiaokang Dai, Puyi Ma, Qian Wang*, Shengjie Ling*, Xiaoxia Yang* and Qing Dai*, In-situ observation of silk nanofibril assembly via graphene plasmonic infrared sensor, Nature Communications, 2024, 15:4643